Pituitary stalk thickening

Causes of pituitary stalk thickening include infiltrative conditions and tumors. A simple mnemonic for recalling the etiology is STALLC.

Causes of a thickened pituitary stalk

The pituitary stalk attaches the pituitary gland to the median eminence of the hypothalamus. The stalk is a critical transit point for hormones secreted by the neurohypophysis (posterior pituitary gland). There are both neoplastic and non-neoplastic causes of a thickened pituitary stalk.

  • Langerhans Cell Histiocytosis (Histiocytosis X)
  • Sarcoidosis
  • Dysgerminoma
  • Infundulohypophysitis
  • Metastasis
  • Tuberculosis
  • Lymphoma
  • Astrocytoma
  • Infundibuloma

A simple mnemonic for thickened pituitary stalk

A simple mnemonic to remember this is STALLC

  • S = Sarcoidosis
  • T = Tuberculosis
  • A = Astrocytoma
  • L = Lymphoma
  • L = Langerhans Cell Histiocytosis (Histiocytosis X)
  • C = Cancer (Metastasis and Dysgerminoma)

References

Turcu AF, Erickson BJ, Lin E, Guadalix S, Schwartz K, Scheithauer BW, Atkinson JL, Young WF Jr. Pituitary stalk lesions: the Mayo Clinic experience. J Clin Endocrinol Metab. 2013 May;98(5):1812-8.

Images(s) Courtesy

MyEndoConsult

Recent Posts

Metanephrines

What are metanephrines? The terms fractionated metanephrines and catecholamines will be defined. In addition, the diagnostic value of metanephrines and catecholamines in the evaluation of

Read More »

Whipple triad

Whipple’s triad Whipple triad is defined as symptomatic hypoglycemia, biochemically confirmed hypoglycemia (plasma glucose <55 mg/dl), and reversal of hypoglycemic symptomatology after correction of hypoglycemia.

Read More »
Table of Contents