Diabetes TrialsDCCT, UKPDS33,D2d, PROACTIVE, ELIXA, DPP, EDIC etc. Bone & Calcium TrialsHORIZON, FRAME, FREEDOM, FIT, ACTIVE etc. Lipids & Obesity TrialsLook AHEAD, ORIGIN N-3, IMPROVE-IT, ODYSSEY OUTCOMES etc. Thyroid TrialsTABLET, ZETA, DECISION etc. Repro Endo TrialsELITE, KEEPS,AMIGOS, WHI E+P, HERS etc. CV TrialsSPRINT, DAPA-HF, LEADER, EMPA-REG OUTCOMES etc Landmark Trials Know the most important clinical trials in endocrinology. Rationale Clinical equipoise (i.e lack of consensus in the scientific community) is the usual starting point for most randomized trials. Poster style presentation Simplified poster style illustrations to facilitate a review of the core message in each landmark trial Practice changing pearls Emphasis is placed on not only the key message of each selected trial but also its impact in terms of guideline recommendations. PICO Model All visual illustrations are presented in the standard P.I.C.O model i.e Population, Intervention, Comparison and Outcomes. Click here for landmark trials